An approved small molecule therapeutic has shown efficacy in numerous target organs of interest in clinical trials. The client wished to show that this efficacy was explained by high drug penetration into these tissues.
PBPK modeling can be utilized in multiple stages of drug development. New guidance from regulatory agencies has highlighted key areas for the use of PBPK models, showing their ever-growing acceptance. Allucent scientists can help you untangle the complex data requirements of PBPK models, and bring these powerful modeling tools to bear on complex problems facing drug development.
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